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On 9/26/23 5:28 PM, Ron Dean wrote:
> Mark Isaak wrote:
>> On 9/25/23 7:41 PM, Ron Dean wrote:
>>> Mark Isaak wrote:
>>>> On 9/25/23 12:32 PM, Ron Dean wrote:
>>>> [...]
>>>>> I think I have! You might mention a few `beneficial mutations", but
>>>>> the
>>>>> detrimental mutations outnumber them hundreds to one.
>>>>
>>>> Can you back that up? In E.coli, one in ten functional mutations
>>>> are beneficial[*]. I`m not sure what the ratio is in humans and
>>>> other animals, but my impression is that the ratio harmful / neutral
>>>> / beneficial mutations is around 15:300:1. I am probably way off,
>>>> but probably not as far off as you.
>>>
>>>
>>> Wikipedia list 6,000 genetic diseases and disorders. I searched for
>>> a list of beneficial mutations, and found no such list. I know you and
>>> a few others can list a handful of beneficial mutations, but they are
>>> vastly outnumbered by determental mutations and the genetic diseases
>>> and disorders they cause.
>>>
>>> https://en.wikipedia.org/wiki/List_of_genetic_disorders
>>>>
>>>> [*] L. Perfeito et al., 2007. Adaptive mutations in bacteria: High
>>>> rate and small effects. Science 317: 813-815.
>>
>> Have you never heard of selection bias? Your numbers mean nothing.
>>
> Not my numbers, I provided a reference.
You provided an irrelevant reference and a number which means nothing in
the context you brought up.
--
Mark Isaak
"Wisdom begins when you discover the difference between `That
doesn`t make sense` and `I don`t understand.`" - Mary Doria Russell
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